| Bufflehead | Bucephala | albeola | | 1 | Anatidae | Anseriformes | Aves | Animalia |
| Riley's 13-Year Cicada | Magicicada | tredecim | | 3 | Cicadidae | Hemiptera | Insecta | Animalia |
| Dogwood Sawfly | Macremphytus | tarsatus | | 1 | Tenthredinidae | Hymenoptera | Insecta | Animalia |
| Delicate Cycnia Moth | Cycnia | tenera | | 1 | Erebidae | Lepidoptera | Insecta | Animalia |
| Great Purple Hairstreak | Atlides | halesus | | 1 | Lycaenidae | Lepidoptera | Insecta | Animalia |
| Gulf Fritillary | Agraulis | vanillae | | 1 | Nymphalidae | Lepidoptera | Insecta | Animalia |
| Gray Petaltail | Tachopteryx | thoreyi | | 1 | Petaluridae | Odonata | Insecta | Animalia |
| Cedar Apple Rust | Gymnosporangium | juniperi-virginianae | | 1 | Gymnosporangiaceae | Pucciniales | Pucciniomycetes | Fungi |
| Skunk Cabbage | Symplocarpus | foetidus | | 1 | Araceae | Arales | Magnoliopsida | Plantae |
| Chicory | Cichorium | intybus | | 1 | Asteraceae | Asterales | Magnoliopsida | Plantae |
| Virginia Dwarf Dandelion | Krigia | virginica | | 2 | Asteraceae | Asterales | Magnoliopsida | Plantae |
| Clasping Venus Looking-glass | Triodanis | perfoliata | | 1 | Campanulaceae | Asterales | Magnoliopsida | Plantae |
| Deptford Pink | Dianthus | armeria | | 1 | Caryophyllaceae | Caryophyllales | Magnoliopsida | Plantae |
| Japanese Knotweed | Reynoutria | japonica | | 1 | Polygonaceae | Caryophyllales | Magnoliopsida | Plantae |
| Spotted Wintergreen | Chimaphila | maculata | | 1 | Ericaceae | Ericales | Magnoliopsida | Plantae |
| Pinxter Flower | Rhododendron | periclymenoides | | 1 | Ericaceae | Ericales | Magnoliopsida | Plantae |
| Sidebeak Pencilflower | Stylosanthes | biflora | | 1 | Fabaceae | Fabales | Magnoliopsida | Plantae |
| Indian Hemp | Apocynum | cannabinum | | 1 | Apocynaceae | Gentianales | Magnoliopsida | Plantae |
| Lyre-leaved Sage | Salvia | lyrata | | 2 | Lamiaceae | Lamiales | Magnoliopsida | Plantae |
| Turk's-cap Lily | Lilium | superbum | | 2 | Liliaceae | Liliales | Magnoliopsida | Plantae |
| Pink Lady's Slipper | Cypripedium | acaule | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Downy Rattlesnake Plantain | Goodyera | pubescens | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Large Whorled Pogonia | Isotria | verticillata | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Southern Twayblade | Neottia | bifolia | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Small Green Wood Orchid | Platanthera | clavellata | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Crested Yellow Orchid | Platanthera | cristata | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Green-fringed Orchid | Platanthera | lacera | | 1 | Orchidaceae | Orchidales | Magnoliopsida | Plantae |
| Purpletop Tridens | Tridens | flavus | | 1 | Poaceae | Poales | Magnoliopsida | Plantae |
| Mayapple | Podophyllum | peltatum | | 1 | Berberidaceae | Ranunculales | Magnoliopsida | Plantae |
| Black Cherry | Prunus | serotina | | 1 | Rosaceae | Rosales | Magnoliopsida | Plantae |
| Wineberry | Rubus | phoenicolasius | | 1 | Rosaceae | Rosales | Magnoliopsida | Plantae |
| Common Mullein | Verbascum | thapsus | | 1 | Scrophulariaceae | Scrophulariales | Magnoliopsida | Plantae |
| Royal Fern | Osmunda | regalis | | 1 | Osmundaceae | Osmundales | Polypodiopsida | Plantae |